Detalhe da pesquisa
1.
First-in-class MKK4 inhibitors enhance liver regeneration and prevent liver failure.
Cell
; 187(7): 1666-1684.e26, 2024 Mar 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-38490194
2.
HilE represses the activity of the Salmonella virulence regulator HilD via a mechanism distinct from that of intestinal long-chain fatty acids.
J Biol Chem
; 299(12): 105387, 2023 Dec.
Artigo
em Inglês
| MEDLINE | ID: mdl-37890783
3.
Virtual Screening Assisted Search for Inhibitors of the Translocated Intimin Receptor of Enteropathogenic Escherichia Coli.
Chembiochem
; 25(2): e202300638, 2024 01 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-37971396
4.
Aminopyrimidine Derivatives as Multiflavivirus Antiviral Compounds Identified from a Consensus Virtual Screening Approach.
J Chem Inf Model
; 64(2): 393-411, 2024 Jan 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-38194508
5.
Filling the Blank Space: Branched 4-Nonylphenol Isomers Are Responsible for Robust Constitutive Androstane Receptor (CAR) Activation by Nonylphenol.
Environ Sci Technol
; 58(16): 6913-6923, 2024 Apr 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-38593436
6.
Structural Features Affecting the Interactions and Transportability of LAT1-Targeted Phenylalanine Drug Conjugates.
Mol Pharm
; 20(1): 206-218, 2023 01 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-36394563
7.
Sodium-Dependent Neutral Amino Acid Transporter 2 Can Serve as a Tertiary Carrier for l-Type Amino Acid Transporter 1-Utilizing Prodrugs.
Mol Pharm
; 20(2): 1331-1346, 2023 02 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-36688491
8.
Direct pathway cloning and expression of the radiosumin biosynthetic gene cluster.
Org Biomol Chem
; 21(23): 4893-4908, 2023 06 14.
Artigo
em Inglês
| MEDLINE | ID: mdl-37259568
9.
Machine Learning-Boosted Docking Enables the Efficient Structure-Based Virtual Screening of Giga-Scale Enumerated Chemical Libraries.
J Chem Inf Model
; 63(18): 5773-5783, 2023 09 25.
Artigo
em Inglês
| MEDLINE | ID: mdl-37655823
10.
In Vitro Identification and In Vivo Confirmation of Inhibitors for Sweet Potato Chlorotic Stunt Virus RNA Silencing Suppressor, a Viral RNase III.
J Virol
; 95(12)2021 05 24.
Artigo
em Inglês
| MEDLINE | ID: mdl-33827953
11.
SARS-CoV-2-host proteome interactions for antiviral drug discovery.
Mol Syst Biol
; 17(11): e10396, 2021 11.
Artigo
em Inglês
| MEDLINE | ID: mdl-34709727
12.
Structure of POPC Lipid Bilayers in OPLS3e Force Field.
J Chem Inf Model
; 62(24): 6462-6474, 2022 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-36044537
13.
Do Go Chasing Waterfalls: Enoyl Reductase (FabI) in Complex with Inhibitors Stabilizes the Tetrameric Structure and Opens Water Channels.
J Chem Inf Model
; 62(22): 5746-5761, 2022 11 28.
Artigo
em Inglês
| MEDLINE | ID: mdl-36343333
14.
Structure-Based Identification of Naphthoquinones and Derivatives as Novel Inhibitors of Main Protease Mpro and Papain-like Protease PLpro of SARS-CoV-2.
J Chem Inf Model
; 62(24): 6553-6573, 2022 12 26.
Artigo
em Inglês
| MEDLINE | ID: mdl-35960688
15.
Synthesis and evaluation of 1,2,3-dithiazole inhibitors of the nucleocapsid protein of feline immunodeficiency virus (FIV) as a model for HIV infection.
Bioorg Med Chem
; 68: 116834, 2022 08 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-35653871
16.
Comparative Modelling of Organic Anion Transporting Polypeptides: Structural Insights and Comparison of Binding Modes.
Molecules
; 27(23)2022 Dec 03.
Artigo
em Inglês
| MEDLINE | ID: mdl-36500622
17.
DeepCDA: deep cross-domain compound-protein affinity prediction through LSTM and convolutional neural networks.
Bioinformatics
; 36(17): 4633-4642, 2020 11 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-32462178
18.
Structural Characterization of LsrK as a Quorum Sensing Target and a Comparison between X-ray and Homology Models.
J Chem Inf Model
; 61(3): 1346-1353, 2021 03 22.
Artigo
em Inglês
| MEDLINE | ID: mdl-33683884
19.
Molecular characteristics supporting l-Type amino acid transporter 1 (LAT1)-mediated translocation.
Bioorg Chem
; 112: 104921, 2021 07.
Artigo
em Inglês
| MEDLINE | ID: mdl-33933805
20.
Docking-Based 3D-QSAR Studies for 1,3,4-oxadiazol-2-one Derivatives as FAAH Inhibitors.
Int J Mol Sci
; 22(11)2021 Jun 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-34204026